Scientific Program

Conference Series Ltd invites all the participants across the globe to attend World Congress on Probiotics, Functional food and Nutraceuticals Singapore.

Day 1 :

Conference Series Probiotics Asia Pacific 2019 International Conference Keynote Speaker Ozlem Tokusoglu photo
Biography:

Ozlem Tokusoglu has completed her PhD from Ege University, Department of Food Engineering. She is currently working as an Associate Professor, Faculty Member in Celal Bayar University Engineering, Faculty Department of Food Engineering. She was a Visiting Scholar at the Food Science and Nutrition Department, University of Florida, USA. She has published many papers in peer reviewed journals and serving as an Editorial Board Member of selected journals. She has published the scientific edited three international books entitled Fruit and Cereal Bioactives: Chemistry, Sources and Applications and Improved Food Quality with Novel Food Processing by CRC Press, Taylor & Francis, USA Publisher, and third book Food By-Product Based Functional Food Powders by CRC Press.

Abstract:

It is recommended drinking six to eight glasses of water per day owing to water makes up 60 percent of our total body weight but many people find staying adequately hydrated to be a challenging task. Recently, there has been growing recognition of the key role of foods and beverages in disease prevention and treatment. Especially, the production and consumption of functional beverages has gained much importance as their providing a health benefit beyond the basic nutritional functions. Functional beverages include an ingredient that gives that food health-promoting property over and above its usual nutritional value. Those may classified as fruit and vegetable based functional beverages, probiotic dairy beverages and fortified beverages with bioactives. With current trends, their functional properties, anticarcinogenic implications have been increased based on commercial demands. Functional beverages can be manufactured directly from fresh fruit and vegetables included bioactive or can be formulated by bioactive enhancing and fortifying. Bioactive compounds potentially extractable from the aimed plant foods and plant byproducts contain majorly phytochemicals, fibers, natural flavor constituents, sugars, polysaccharides, proteins and its derivatives and can be fortified to beverages and called fruit and vegetable functional drinks, if fortify by protein concentrate, whey protein isolate, milk protein concentrate, probiotic addition and other dairy ingredients, they are called as dairy functional beverages. Also dairy functional drinks can be manufactured for human health. Bioactives in dairy beverages have many functions as antimicrobial, antithrombotic, antihypertensive, opioid, immunomodulatory, antioxidant related to gastrointestinal system, cardiovascular system, nervous and immune systems. Bioactive constituents as anticarcinogenic peptides are associated with chemopreventive properties, reduction of tumor proliferation as well as apoptosis. Cytotoxic milk peptide lactoferrin (whey proteins) showed positive efficiency against cancer cells. Breast cancer treatment based on the lactoferrin utilization which results the inhibition of cancer cells through suppressing signaling of nasopharyngeal carcinoma cells. Peptides derived from beta-casein (isoleucine-proline and valine-proline-proline) have been acted the hypertensive ability and characterized as potentially effective against cardiovascular diseases. Dietary casein and whey-based milk peptides and protein hydrolysates showed a vital role in maintaining immune system by the IgG antibodies production inducing the proliferation of spleen lymphocytes through mitogen inhibition, depending upon the availability of sialic acid. At present, beverages are the most active functional food category due to their convenience and possibility to meet consumer demands for container contents, size, shape, and appearance, as well as ease of distribution and storage for refrigerated and shelf-stable products. The design and development strategies of functional beverages requires multistage processing which takes into account various parameters including organoleptic acceptance, physical and microbial stability, chemical and functional properties, cost and distributing strategies. From the nutrition perspective, functional and nutraceutical beverages has been increased great attention for healthy and safe bioactive constituent utilization.

Conference Series Probiotics Asia Pacific 2019 International Conference Keynote Speaker Debabrata Biswas photo
Biography:

Debabrata Biswas is a leading scientist at University of Maryland, USA. Debabrata Biswas completed PhD from University of Tokyo. Dr. Biswas’s research projects focused on the reduction of pre- and post-harvest levels of colonization and contamination these foodborne bacterial pathogens in foods specifically meat and meat products and development of vaccines that prevent colonization of animals by E. coli O157, C. jejuni and Salmonella enterica species which may reduce human gastrointestinal infections

Abstract:

Problem Statement: Campylobacter is one of the most common causes of foodborne illness in the US and Europe. More than 90% of cases of campylobacteriosis are caused by Campylobacter jejuni (CJ). Poultry and poultry products are major sources of campylobacteriosis. Appropriate measure to reduce the colonization of CJ in chicken gut is required to control campylobacteriosis.

Approach: Recently, we found that in the presence of prebiotic-like components (peanut flour), production of metabolites specifically Linoleic Acid (LA) by Lactobacillus casei (LC) increased 100 folds and that higher concentration of LA could outcompete several enteric pathogens, including CJ. Therefore, we developed a genetically engineered LC strain by overexpressing linoleate isomerase (mcra, myosin cross-reactive antigen) gene and named as LC+mcra. We also verified the ability of LC+mcra to inhibit CJ growth, adhesion and invasion of chicken cells with or without natural poultry growth promoter, such as Berry Pomace Extracts (BPE).

Results: Both LC+mcra itself and its byproducts inhibited the growth of CJ more than 6 logs within 48 hours. We also found that LC+mcra and its byproducts reduced both adherence and invasion ability of CJ to the chicken macrophage (HD-11) and fibroblast (DF-1) cells, altered the expression of virulence genes (ciaB, cdtB, cadF, flaA and flab) and physiological properties (motility and hydrophobicity) of CJ. In mixed culture condition, LC+mcra with CJ in the presence of BPE amplified these effects including CJ growth inhibition (>3 log CFU/mL) and disrupting host cells-CJ interactions. Cell-Free Cultural Supernatant (CFCS) of LC+mcra in the presence of BPE also showed reduction of CJ growth, interaction of CJ with DF-1 and HD-11 cells and expression of multiple CJ virulence genes.

Conclusion: This finding indicates that BPE and LC+mcra in combination might be able to prevent colonization of CJ in poultry and reduce cross-contamination in poultry products that cause campylobacteriosis in human.

 

Keynote Forum

Osama Ibrahim

BioInnovation, USA

Keynote: The nature and manufacturing of Probiotics/Prebiotics for gastrointestinal health

Time : 11:50-12:35

Conference Series Probiotics Asia Pacific 2019 International Conference Keynote Speaker Osama Ibrahim photo
Biography:

Osama Ibrahim is a highly experienced, principal research scientist with particular expertise in the field of microbiology, molecular biology, food safety, and bio-processing for both pharmaceutical and food ingredients. He is knowledgeable in microbial screening /culture improvement; molecular biology and fermentation research for antibiotics, enzymes, therapeutic proteins, organic acids and food flavors, biochemistry for metabolic pathways and enzymes kinetics, enzymes immobilization, bio-conversion, and analytical biochemistry. He was external research liaison for Kraft Foods with Universities for research projects related to molecular biology and microbial screening and holds three bioprocessing patents. In January 2005, he accepted an early retirement offer from Kraft Foods and in the same year he formed his own biotechnology company providing technical and marketing consultation for new start up biotechnology and food companies.

Abstract:

Probiotics are live bacteria such as bifidobacteria and lactic acid bacteria that are beneficial for gastrointestinal health. These probiotics bacteria intended to be colonized in the large intestine (colon) and reduce the effect of harmful and pathogenic bacteria in the digestive system, suggesting that these probiotics bacteria can prevent gastrointestinal tract from infection diseases and reduce colon inflammation. It is also assumed that probiotics bacteria strengthen the immune system. Prebiotics are non-digestible carbohydrates by digestive enzymes in small intestine and are fermentable when reached the clone. This fermentation process of prebiotics enhances the growth of beneficial bacteria (probiotics) in the colon. There are two categories of prebiotics: Prebiotics fibers that are naturally occurred in whole grain, broccoli, asparagus, radish, cabbage, etc. and prebiotics oligosaccharides such as Fracto-Oligosaccharide (FOX), Galacto-Oligosaccharides (GOS), Xylo-Oligisaccharides (XOS), etc. These prebiotics oligosaccharides are manufactured enzymatically from plant sources. Synbiotics concept was first introduced as a mixture of probiotics and prebiotics that beneficially affect the gastrointestinal tract of the host (human or animals). This synbiotic formulation that contains both probiotics and prebiotics are manufactured by using microencapsulation technology and are marketed in the form of capsules or tablets. Manufacturing of probiotics/prebiotics and the impact of this synbiotics relationship on colon health will be highlighted.

  • Prebiotics & Probiotics | Nutraceuticals vs Dietary Supplements | Nutrition and Food Sciences | Functional Food and Bioactives
Location: Holiday Inn Singapore Atrium: Seletar Room 3, Level 3
Speaker

Chair

Ozlem Tokusoglu

Celal Bayar University, Turkey

Session Introduction

Gunjan Goela

Gunjal Kitchen, India

Title: Essence of Vegetarian cuisine

Time : 12:35-13:05

Biography:

Gunjan Goela have been a chef for more than 18 years and had the privilege to cook for our pm Mr. Narendra Modi along with the presidents and dignitaries of various countries, recently in Mumbai for make in india.She had done a major catering for Mr. L N Mittals dinner in London. At present too she is in Antalya catering for 5,000 guests for a grand wedding also Had catered to some of the most important Indian industrialist like Ambanis, Gcoenkas, Modis, and Birlas. She was invited by the Italian govt. to be a speaker on Principals of Ayurveda consecutively for 4 years. Held workshops on demonstrating Indian food in Turin at Slow Food Congress with the audience of 1500 people

Abstract:

Early human food cultures were mainly plant based. Major religions like Hinduism and Buddhism have recommended a vegetarian way of life since its beginning. The history of the vegetarian nutrition started from the earlier times in the 6th century BC by Orphic mysteries followers. Also the Greek philosopher Pythagoras is considered as the father of ethical vegetarianism. The Script Pythagorean way of life was followed by a number of important personalities and influenced the concept of Vegetarian nutrition. In the European world vegetarian nutrition started disappearing during the middle Ages and in the period of Renaissance and the Age of Enlightenment many famous personalities started practicing vegetarian way of life since 1847. A vegetarian diet is comprised of non-consumption of any form of meat which is inclusive of cattle, poultry, fish etc. this mode of vegetarian consumption is increasing in the world rapidly. The largest community of vegetarian food practice happens in India; also a large number of people are now thriving for vegetarian diet in countries like UK, USA, Germany and many more western countries. Currently many European nutrition advisors accept that a vegetarian diet is nutritionally sound, balanced and consists of a proper balanced diet Many claim that a meal without meat protein and animal fat we do not fulfil the criteria of a fully-fledged healthy diet but vegetarian diet is a winner for health and our health is supplemented best with nature’s abundance of greens and it also helps us overcome the problems associated with macro and micro-nutrients. Vegetarian diet is a boon for our healthy life as it helps in reducing cholesterol level, reducing body weight, lower blood pressure and also helps our body in reducing cardiovascular diseases and chronic diseases like diabetes and cancer.

Biography:

Ozlem Tokusoglu has completed her PhD from Ege University, Department of Food Engineering. She is currently working as an Associate Professor, Faculty Member in Celal Bayar University Engineering, Faculty Department of Food Engineering. She was a Visiting Scholar at the Food Science and Nutrition Department, University of Florida, USA. She has published many papers in peer reviewed journals and serving as an Editorial Board Member of selected journals. She has published the scientific edited three international books entitled Fruit and Cereal Bioactives: Chemistry, Sources and Applications and Improved Food Quality with Novel Food Processing by CRC Press, Taylor & Francis, USA Publisher, and third book Food By-Product Based Functional Food Powders by CRC Press.

Abstract:

Robotic surgery is a type of minimally invasive surgery. Minimal invasive means that instead of operating on patients through large incisions, it has been used miniaturized surgical instruments which fit through a series of quarter-inch incisions. When performing surgery with the Da Vinci Si - the world’s most advanced surgical robot; these miniaturized instruments are mounted on four separate robotic arms, allowing the surgeon maximum range of motion and precision and has 3D camera. Robotic surgeries provide fewer traumas on the body, minimal scarring and faster recovery time. Medical nutrition therapy comprehends oral nutritional supplements, enteral or parenteral nutrition after surgery. To acquire convenient healing and functional recovery, a metabolic response is indispensable, but this needs nutritional therapy especially when the patient is malnourished and the stress/inflammatory reply are prolonged. Nutrition therapy is the verdict of nutrition or nutrients either orally including regular diet, therapeutic diet, fortified food, oral nutritional supplements or by Enteral Nutrition (EN) or Parenteral Nutrition (PN) to cure or treat malnutrition. In order to reduce perioperative discomfort including anxiety oral preoperative carbohydrate treatment (instead of overnight fasting) the night before and two hours before surgery should be administered. After operation, especially for gastrointestinal system, the intake of a hypoosmolar 12.5% carbohydrate rich drink has been shown to reduce postoperative insulin resistance. After minimal invasive surgery, oral preconditioning with glutamine, antioxidants and green tea extract versus placebo elevated plasma vitamin C concentrations significantly improved and improved total endogenous antioxidant capacity without reducing oxidative stress and inflammatory response. It can be difficult to bounce back after an operation, but a number of vitamins, minerals and antioxidant nutrients can support the recovery of patient after minimal invasive surgery operations. Studies have shown that long used vitamin K, which promotes blood clotting, to help heal incisions in patients after surgery and also aids in building strong bones. Vitamin K1 is present in many foods, especially leafy green vegetables including cabbage and spinach, broccoli, brussels sprouts, spring onions and is also present in liver, cows’ milk, egg yolk and some cereals. With antioxidant properties many times more powerful than those found in better-known nutrients (including vitamin C and vitamin E), grape seed extract is a heart-smart and cancer-smart botanical.

Osama Ibrahim

BioInnovation, USA

Title: Dietary supplements and its legal regulations

Time : 14:35-15:05

Biography:

Osama Ibrahim is a highly experienced, principal research scientist with particular expertise in the field of microbiology, molecular biology, food safety, and bio-processing for both pharmaceutical and food ingredients. He is knowledgeable in microbial screening /culture improvement; molecular biology and fermentation research for antibiotics, enzymes, therapeutic proteins, organic acids and food flavors, biochemistry for metabolic pathways and enzymes kinetics, enzymes immobilization, bio-conversion, and analytical biochemistry. He was external research liaison for Kraft Foods with Universities for research projects related to molecular biology and microbial screening and holds three bioprocessing patents. In January 2005, he accepted an early retirement offer from Kraft Foods and in the same year he formed his own biotechnology company providing technical and marketing consultation for new start up biotechnology and food companies.

Abstract:

Dietary supplements are products intended to supplement the diet and are not drugs for disease treatments. They are vitamins, minerals, herbals, botanicals, amino acids, enzymes, metabolites and many other products. Some supplements play an important role in health, for example calcium and vitamin D are important for keeping bones strong and folic acid is important for pregnant women to prevent certain birth defect in their babies. Dietary supplements are available in the market in the form of tablets, capsules, soft gels, gel caps, powders, drinks and energy bars. These dietary supplements do not have to be approved by the U.S. Food and Drug Administration (FDA) before marketing as required for prescription drugs or over-the counter drugs but manufacturers must register their manufacturing facilities with the FDA and are responsible to having evidence that their dietary supplement products are safe and label claims are not misleading. With a few well define exceptions dietary supplements such as pre-workout for athletics and weight loss products may only be marketed to support structure or function of the body, without claiming to treat a disease or condition and must include a label that highlight “These statements have not been evaluated by FDA and this product is not intended to diagnose, treat, cure or prevent any diseases”. Popular dietary supplements including safety and risks will be highlighted.

Biography:

Nilesh Thakor has completed MD in Community Medicine from Gujarat University, India. He is an Associate Professor in Department of Community Medicine, GMERS Medical College, Vadnagar, Gujarat, India. He has published more than 70 papers in reputed journals

Abstract:

Background: Childhood obesity itself is a predictor of adult obesity and of higher than expected adult morbidity and mortality. Due to difficulty in the treatment of obesity in adults and the many long-term adverse effects of childhood obesity, prevention of childhood obesity has now been recognized as a public health priority.

Objective: To know the prevalence and determinants of obesity in school children of Ahmedabad city.

Methodology: The present cross-sectional study was undertaken during July 2009 to April 2011 in randomly selected 10 schools of Ahmedabad city, Gujarat by Department of Pediatrics and Community Medicine of GMERS Medical College, Dharpur, Patan. Total 2562 children between the age group of 10 to 15 years were examined after taking written informed consent of their parents using pre-designed, pre-tested, semi-structured performa. Anthropometric measurements were taken and BMI were calculated. The prevalence of overweight and obesity were determined based on the IOTF (International Obesity Task Force) criteria. Various determinants of obesity and overweight were studied by interviewing children. Thus collected data was analyzed using SPSS 17 (Trial version).

Results: Out of 2562 children males were 54.09% and females were 45.9%. Prevalence of obesity and overweight was 5.62% and 9.99%, respectively. Overall prevalence of obesity was more among female population (6.8%) as compared to that in males (4.62%). The prevalence of obesity was found to be highest among 15 years age group (8.22%). The prevalence of obesity and overweight was significantly higher amongst less active group (9.3% and 13.95%, respectively) as compared to more active group. Prevalence of obesity and overweight was significantly higher in the group of children who spent >2 hours daily in front of television or computers. The prevalence of obesity and overweight was significantly higher amongst group of children who took daily calories above RDA (18.57% and 15.19%, respectively) as compared to the other group. The prevalence of obesity and overweight was significantly higher in them (8.91% and 13.36%) as compared to those who took junk food less than or equal to two times per week (1.71% and 5.98%, respectively). The prevalence of obesity and overweight among children having parents with history of obesity was 46.15% and 17.94%, respectively which was significantly higher than those without parental history of obesity (4.34% and 9.74%).

Conclusion: High prevalence of obesity and overweight in school children indicate an urgent need to increase awareness via education and motivation of all stakeholders.

Biography:

Sunil Nayak is a Pofessor & Head, Assistant Professor, Department of Community Medicine, GMERS Medical College, Vadnagar, Gujarat, India.

 

Abstract:

Background: Adolescence and young adulthood are periods of critical development and transition. Adolescent constitutes over 23% of the population in India. Nutrition and health needs of the adolescent are more because of more requirements for growth spurt and increase in physical activity.

Objective: To study prevalence of anemia and visual impairment among school going adolescents of Patan city, Gujarat.

Methodology: The study was carried by Community Medicine Department, GMERS Medical College, Dharpur, Patan during period from September 2014 to August 2015. After taking the permission of principals of 9 schools and consent of the parents of adolescents, 841 adolescents from 10 schools of Patan city were examined for anemia and visual impairment. The data was collected by predesign, pretested proforma and analyzed using SPSS 17.0 (Trial Version).

Results: Mean age was 15.8±1.96 years. Out of 841, 432 (51.4%) were boys and 409 (48.6%) were girls. The study revealed that 67.0% girls were suffering from anemia compare to 58.7% of boys. 117 (13.9%) adolescents had visual impairment.

Conclusion: High prevalence of anemia and visual impairment among these adolescents needs great attention and health education.